Author's response to reviews Title: Identification of Biomarkers in Ductal Carcinoma in situ of the Breast with microinvasion Authors:

Immunohistochemical Evaluation of Human p53 Tumor Suppressor Protein Content in Ductal Carcinoma in Situ of the Breast

The focus of this study was to determine if early detection of mutant p53 accumulation may be an early indicator of tumor aggressiveness and transformation to invasive breast cancer. For this purpose, the p53 content of 100 human breast biopsies classified as ductal carcinoma (DCIS), was evaluated by immunohistochemical method. All specimens were microscopically classified into histologic types...

Androgen Receptor Analysis in Relation to Estrogen and Progesterone Receptors as well as Histological Grade for Ductal Carcinoma In Situ of the Breast

Background and Objective: Since the advent of mammography screening, ductal carcinoma in situ (DCIS) of the breast has been diagnosed increasingly. In contrast to the situation in invasive breast carcinoma, there are only a few reports on androgen receptor (AR) status in DCIS and few reports on estrogen ...

The Expression Of Biomarkers In Invasive Ductal Carcinoma Of Breast Through Tissue Array Method And Its Comparison With Clinicopathologic Features

  Background and Objective: In this study, we explored expression rate, some biomarkers affecting the prognosis of the breast carcinoma, and the relationship between these markers and clinicopathologic features of the disease as well as the relationship between each of these markers through a tissue array technique. Materials and Methods: This study was an observational and cross-sectional st...

Author's response to reviews Title: Is there a role for the quantification of RRM1 and ERCC1 expression in Pancreatic Ductal Adenocarcinoma? Authors:

Insitu paget disease of breast: A case report

Introduction: Mammary Paget’s disease is generally accompanied by in situ ductal carcinoma, consequently, prompt diagnosis and treatment can halt further invasion and yield better prognosis. Case Presentation: The patient was a 39-year old woman, who presented with superficial ulcers and nipple discharge of left breast, She had no palpable mass underneath. The patient was G2 P2 and under oral ...